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Patients with MCS exhibit elevated oxidative status and inflammatory markers compared to their healthy counterparts.[ref] MCS patients also have lower glutathione levels.[ref] Glutathione is a naturally produced antioxidant and one of the main ways that our cells fight oxidative stress

Its also why many protocols suggest administration before sleep, to align with and enhance the body's natural GH pulse during the night, turning this potential side effect into a synergistic benefit for sleep quality studies

A mixed-methods analysis of the effects of N-acetylcysteine

the number of ROS produced by damaged mitochondria may exceed the processing capacity of the mitophagy machinery, and in some cases, mitophagy may even promote cell death