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BPC-157 is a 15-residue, 1419.53 g/mol pentadecapeptide whose mechanistic literature centres on local angiogenic signalling, Hsieh and colleagues (J Mol Med, 2017) reported upregulation and internalisation of VEGFR2 in human endothelial cells, and Chang and colleagues (J Appl Physiol, 2011) reported increased FAK and paxillin phosphorylation with greater outgrowth and migration in cultured rat tendon fibroblasts

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Post-hoc test showed that the comparison between Groups 1 and 2 was significant, while the comparison between all other groups was statistically non-significant (Table 1, D)

Potential Benefits: Significant Weight Loss: When combined with GLP-1 therapy, Cagrilintide has led to greater reductions in body weight than GLP-1s alone in clinical trials