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The platform enabled efficient loading of an oligo-PROTAC (DFUS-PS9C), conjugated via click chemistry to an E3 ligase ligand, facilitating targeted ubiquitination and degradation of FUS protein, a strategy with significant implications for PROTAC-based therapies in neurodegenerative diseases

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Patients who add sermorelin without adjusting training or protein intake see minimal body composition benefit compared to semaglutide alone