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Hendershot et al., 2025

Even more impressive, over 85% of participants receiving the two highest retatrutide doses achieved complete resolution of steatosis, defined as liver fat content dropping below 5%

After discontinuing its internal GLP-1 in May of 2025 for causing liver issues, Pfizer won a bidding war against seven other companies for Metsera, which is developing a variety of incretin assets, paying $10 billion in one of 2025s largest M&A deals

A common pattern is thigh, abdomen, thigh, abdomen, rotating left and right within each region