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While orforglipron as a small molecule could potentially be compounded after patent considerations, the regulatory landscape around compounding is complex and evolving

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It also notes that repeated thawing and refreezing can damage peptides, and that moisture, oxygen, and temperature changes can affect stability

Food and Drug Administration (FDA) has added a new warning to the weight-loss medication Wegovy, highlighting potential gastrointestinal reactions and stressing that individuals with severe gastroparesis should not take Wegovy