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The SURMOUNT-5 trial directly compared the two medications and found tirzepatide produced approximately 20 percent weight loss compared to 14 percent for semaglutide

13 Table 2: Signs and Symptoms of Semaglutide Overdose 12 Feeling lightheaded or dizzy Feeling shaky or jittery Sweating, chills and clamminess Irritability or impatience Headache Weakness Fatigue Nausea and/or vomiting Seizures Altered Mental Status Syncope/Near Syncope Hypotension Lastly, it is important to note that most calls for help related to semaglutide overdoses are from adults ages 40-70, with the largest group in the 60 to 69 range

What Are GLP-1 Shots

Today, there are several GLP-1s on the market including semaglutide, dulaglutide, exenatide and liraglutide