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Description

This mimics the amplitude and frequency of GH pulses seen in much younger individuals

Twice-daily application shows visible improvement within 4-6 weeks

Data availability The datasets generated and/or analysed during the current study are available from the corresponding author on reasonable request

Rapid amplification of cDNA ends (RACE) was performed using 5-Full RACE Core Set (Takara) and 3-Full RACE Core Set (TaKaRa), according to the manufacturers protocols