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Pemvidutide (ALT-801) is another unimolecular once weekly GLP-1/glucagon agonist undergoing a phase 2 trial as obesity treatment, following a phase 1 trial demonstrating up to 10.3% WL at 12 weeks [73]

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Instead, Sheer underscores the importance of discussing heart disease risk reduction including weight management, physical activity, blood pressure control, and appropriate medication options with a healthcare provider

Lillys phase 2 retatrutide trial achieved up to 17.5% mean weight reduction at 24 weeks