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These long haulers commonly experience one or more of the following symptoms, some of which can be debilitating: A pins-and-needles sensation Changes in period cycles Chest or stomach pain Cough Diarrhea Difficulty breathing or shortness of breath Difficulty thinking or concentrating (sometimes referred to as brain fog ) Dizziness upon standing (lightheadedness) Fever Headache Heart palpitations (heart beating fast or pounding) Joint or muscle pain Lost or diminished sense of smell or taste Mood changes Rash Sleep problems Symptoms that get worse after physical or mental activities Tiredness or fatigue Officially, COVID-19 long haulers are said to suffer from PASC, which is short for post-acute sequelae of SARS-CoV-2

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Expectedly, LDLR / mice exhibited significantly reduced hepatic LDLR levels compared with those of the wild-type mice (Figures 4B,C)