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Some people may also feel like their entire body is swollen, notes MedlinePlus

PMC 2390769

Common triggers include soaps, detergents, stress, temperature changes, and allergens like pollen or pet dander

In addition to multifocal lesions in MS, in a recent study using fluorescence spectroscopy using the solvatochromic lipid probe Nile Red, we reported diffuse changes in myelin lipid polarity in otherwise normal-appearing MS white matter, which was particularly pronounced in the periventricular areas, again supporting the notion of a myelin toxin circulating in the CSF