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Impaired lung function diminishes oxygen intake, leading to tissue hypoxia, which becomes more pronounced during chronic obstructive pulmonary disease (COPD) exacerbations, potentially causing elevated levels of circulating uric acid resulting from damage to the lungs and surrounding tissues

It's a naturally occurring copper-binding peptide that directly stimulates collagen I, collagen III, and elastin synthesis the structural proteins that make up the annulus fibrosus

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[DOI] [PMC free article] [PubMed] [Google Scholar] 19.Medvidovic-Grubisic M., Stambolija V., Kolenc D., Katancic J., Murselovic T., Plestina-Borjan I., Strbe S., Drmic D., Barisic I., Sindic A., et al