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Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway
Microglia are elongated, branched cells that monitor their environment and secrete neurotrophic factors in a state of homeostasis
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NAD+ activates DNA repair enzymes, but oxidative damage can accumulate faster than repair can keep pace when glutathione is low
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