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10.1016/j.jpsychires.2019.10.006 19 LavignaG.MasoneA.BouybayouneI.BertaniI.LucchettiJ.GobbiM.et al (2021)
Without shelterin, exposed telomeric DNA triggers ATM/ATR kinase cascades, p53 activation, and irreversible senescence the same outcome produced by critically short telomeres that can no longer support proper shelterin assembly
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