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IGF-1 LR3 contains a 13-amino-acid N-terminal extension and a glutamic acid substitution at position 3, reducing binding affinity for IGF-binding proteins (IGFBPs) by approximately 100-fold compared to endogenous IGF-1

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Milk Thistle Milk thistle (more specifically, silymarin), while a somewhat common supplement found on supplement store shelves these days, is primarily known for its ability to help support the liver thanks to its naturally high antioxidant properties

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