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In another recent study, researchers found that people taking semaglutide had a higher risk of developing a serious eye condition called nonarteritic anterior ischemic optic neuropathy, which can cause sudden vision loss

One 2024 study at the Smell and Taste Center at the University of Pennsylvania (source) found evidence of GLP1 agonists significantly depressing the perception of all five basic taste qualities. Interestingly, while all participants in the study experienced a slight decline in their sense of smell, it was not considered statistically significant suggesting that olfactory changes may be more individualised, or more complex to detect in standardised tests

Hard endpoints are actual clinical events like heart attacks, strokes, and deaths

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