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This ensures higher bioavailability, allowing more active glutathione to reach the bloodstream and skin cells, maximizing antioxidant and skin-brightening effects

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Lundsen T, Hunt MC, Nilsson LM, Sanyal S, Angelin B, Alexson SE, et al

The authors conducted both a traditional intention-to-treat analysis (termed treatment policy estimand), where outcomes are analyzed regardless of discontinuation or change in treatment dose, which limits bias associated with dropout, as well as an analysis where observations were regardless of change in treatment dose only (trial product estimand)