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A subcutaneous injection uses a shorter needle to inject the B12 solution into the tissue layer between the skin and muscle, but it may be a slower absorption rate than other methods of administration

Higher-dose oral B12 (e.g., 1000 g daily) is sometimes used but should only be considered under clinical supervision with appropriate monitoring, particularly in cases of malabsorption where intramuscular treatment remains the first-line approach in UK practice

If youve had a chronic, severe vitamin deficiency for many years, your symptoms will be more significant than they would be after a few weeks of decreased B12 intake

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