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Furthermore, some studies indicated that genetic variations in FTO could potentially impact weight gain and weight-related diseases by either increasing the amount of food consumed or affecting the regulation of appetite and satiety

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The co-polymerization with biopolymers such as chitosan or cellulose can increase biodegradability, for example, paclitaxel-loaded poly(lactide-co-glycolide) microparticles were developed containing chitosan-sensitive gelling solution for sustained release, which displayed ~ 63% efficiency [141]