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As Bellomo put it, The evidence is approaching the threshold where practical planning should begin in earnest, even as we await data on sustained real-world outcomes. GLP-1 medications may ultimately become an important driver of cardiometabolic health improvement, but translating clinical promise into measurable mortality experience will take years of real-world data

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doi: 10.3389/fphar.2024.1439203 Received 27 May 2024 Accepted 07 August 2024 Published 16 August 2024 Volume 15 - 2024 Edited by Patricia Sue Grigson, The Pennsylvania State University, United States Reviewed by Yada Treesukosol, California State University, United States Hale Yapici Eser, Ko University school of medicine, Trkiye Updates Copyright 2024 Edvardsson, Vestlund, Ericson and Jerlhag

Conversely, insulin dramatically increased the levels of LDL-C and HDL-C in ZDF rats