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The Phase 2b protocol used one dose per day for 12 weeks

The results become meaningful when viewed alongside larger studies on copper peptides and physical scalp stimulation that show consistent positive effects

Since glucocorticoids are known to mediate inhibition of NF-kB (beneficially modulated by certain antioxidants such as thiols), adjunctive therapy with an effective thiol donor (e.g., NAC or SAMe) and vitamin E may optimize control of inflammatory mediator release and cell response as compared to pure immunomodulatory treatment or therapy limited to antioxidants

Arbutin , specifically alpha arbutin, is considered to be an ideal skin lightening agent, says Dr