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Seshadri S, Wolf PA, Beiser A, et al

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The percentage of patients who discontinued due to ineffective therapy was 1.7% in the liraglutide injection 1.8 mg + metformin + rosiglitazone treatment group, 1.7% in the liraglutide injection 1.2 mg + metformin + rosiglitazone treatment group, and 16.4% in the placebo + metformin + rosiglitazone treatment group

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The FDA has approved tirzepatide for use in patients already taking metformin, and major diabetes organizations including the American Diabetes Association recognize this combination as a standard dual-therapy approach

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These structural and functional parallels suggest that Arabidopsis , despite lacking a nervous system, can still provide valuable insights into the molecular principles underlying glutamate receptor-mediated signalling

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