tirzepatide history Both medications work. The real question is which one works better for you. showed 20%+ average body weight loss in trials. Semaglutide, around 15%. Sounds like an easy call, until you Tirzepatide - Wikipedia

All the authors have contributed significantly to the manuscript, per the International Committee of Medical Journal Editors criteria of authorship

Release 168 , 200208 (2013)

Semaglutide and Tirzepatide leverage the power of the gut-brain axis, enhancing appetite control, metabolic balance, and gut flora

(Right) GLP-1 receptor agonist (GLP-1RA) reduces cholesterol accumulation by affecting the expression of genes in the hepato-enteral circulation and cholesterol reverse transport pathway, such as farnesoid X receptor (FXR), fibroblast growth factor-15 (FGF15), fibroblast growth factor receptor 4 (FGFR4), cytochrome P450 family 7 subfamily A member 1 (Cyp7a1), proprotein convertase subtilisin/kexin type 9 (PCSK9), low-density lipoprotein receptor (LDLR), etc