In addition to glucuronidation that is responsible for metabolism of approximately 55% of paracetamol as the major metabolic pathway, approximately 30% of circulating paracetamol may be also conjugated by sulfotransferase, as shown in Fig
When supplemented in combination with methimazole, berberine significantly altered the microbiota composition of patients, decreasing the abundance of the pathogenic bacteria Chryseobacterium indologenes and Enterobacter hormaechei while simultaneously increasing the content of the beneficial bacteria Lactococcus lactis ( 185 )
Statistical Analysis Data were analyzed using Pulsefit (HEKA Elektronik, Lambrecht/Pfalz, Germany), Igor 4.0 (WaveMetrics, Lake Oswego, USA), and SigmaPlot 12.0 (Systat Software, Inc., San Jose, USA)
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