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7 These agents are recommended for patients who do not meet their personalized glycemic targets with metformin and lifestyle changes (or who have a contraindication to metformin) due to its benefits in controlling blood sugar, slowing CKD progression, and reducing cardiovascular disease

[16] [17] Semaglutide (as Wegovy) is further indicated as an adjunct to a reduced-calorie diet and increased physical activity for weight management, including weight loss and weight maintenance, in adults with obesity (initial BMI 30 kg/m 2 ) or who are overweight (initial BMI 27 kg/m 2 ) and have at least one weight-related comorbidity such as dysglycemia (prediabetes or type 2 diabetes), hypertension, dyslipidemia, or cardiovascular disease

PMID 17502622

The smaller-length needle is easier to place more precisely on veins that are especially fragile, small in size, or that roll