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It was also proved that matrix-detached epithelial and cancer cells cluster spontaneously through a pathway involved with Nectin-4 (also known as cell adhesion protein PVRL4), the process of which sustains GPX4 expression and buffers against lipid peroxidation by stimulating the PVRL4/64/Src axis signal pathway (Brown et al., 2018)

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Cell Physiol Biochem 35:20192032 Li L, Sun Q, Li Y et al (2015) Overexpression of SIRT1 induced by resveratrol and inhibitor of miR-204 suppresses activation and proliferation of Microglia

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