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(eClinicalMedicine) found that 52 weeks of once-weekly semaglutide reduced hip bone mineral density by 2.6% and lumbar spine density by 2.1% compared to placebo, with increased bone resorption and no compensatory increase in bone formation

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Arai, R

Additionally, the superiority of GLP-1RAs compared to placebo in the primary endpoint of 3-MACE were found with liraglutide in the LEADER trial (HR 0.87