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Head-to-Head: Mechanism Comparison These two compounds represent two fundamentally different theoretical approaches to obesity pharmacology and one of them has clinical proof while the other does not

[10] [11] Another interaction is with thyroid hormones such as levothyroxine

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3 GLUCAGON-LIKE PEPTIDE-1 Despite being identified later than GIP, GLP-1 quickly became the focus of intensive research, such that fewer than 20 years were to elapse between the description of its incretin effect and the approval of the first highly successful GLP-1 RA drug class for treatment of T2D