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This gap has prompted oncologists and primary care providers to explore pharmaceutical interventions that address appetite regulation without interfering with cancer treatment

Cardiovascular outcome trials, once considered ancillary, can strategically reposition metabolic drugs as cardioprotective agents

For example, the weight-loss supplement ephedra was banned in 2004 only after reports of serious side effects, including heart attacks and induced psychosis, some even resulting in death

Psychoneuroendocrinology 15, 371379.10.1016/0306-4530(90)90062-E 19 BaranowskaB.RadzikowskaM.Wasilewska-DziubinskaE.RoguskiK.BorowiecM