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Key clinical considerations for using onceweekly subcutaneous semaglutide 2.4 mg in clinical practice Currently, onceweekly subcutaneous semaglutide 2.4 mg is approved for use in Canada, Europe, the UK and the USA as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adults with an initial BMI of 30 or 27 kg/m 2 in the presence of 1 weightrelated comorbid condition