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CPMP Opinion following an Article 36 referral Bupropion hydrochloride

Assuming similar structural properties of GLP-1R and GCGR, binding of Fab 3F52 to a closed state of GLP-1R may prevent a conformational change of the ECD relative to the TM domain required for BMS21-induced activation of GLP-1R

BT, W., FB, S., D, C.-T., K, M., IA, M., & PL, G

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