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AOD-9604 targets fat tissue directly without systemic hormonal disruption

While naturally occurring IGF-1 plays a critical role in growth and development, the LR3 modification extends its half-life and dramatically enhances its biological availability making it a favorite for research into athletic performance, muscle rehabilitation, and age-related decline

Chemosphere 262:127905 Liu J, Zhang J, Kim SH, Lee HS, Marinoia E, Song WY (2021) Characterization of Brassica rapa metallothionein and phytochelatin synthase genes potentially involved in heavy metal detoxification

These conversions are imprecise and do not account for metabolic differences between species