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Genetic variability in the methylenetetrahydrofolate reductase gene (MTHFR) affects clinical expression of Wilsons disease

Sleep and circadian alignment stabilize metabolic and redox rhythms that gate ROS detoxification and macromolecular repair, improving resilience to daytime oxidative challenges and environmental hygienelimiting UV/photosensitization in exposed tissues and managing metal exposures that expand the labile iron poolcurbs non-enzymatic ROS generation and Fenton chemistry at their source (Davinelli et al

S.RossingP.von ScholtenB

S., Akatsuka, A., Yoshimura, S