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Preclinical evidence is more mixed, with some animal models showing muscle preservation under certain conditions [3], but the clinical human data from high-risk populations is less reassuring

Science 118 MorizaneA.DoiD.KikuchiT.OkitaK.HottaA.KawasakiT.et al (2013)

Thyroid function typically requires monitoring every 6-12 weeks initially when titrating medications, then every 6 months once stable

The test was intended to assess peak performance and the athlete's ability to sustain exertion over time, a key aspect of endurance performance in sports like swimming