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Survodutide (BI 456906) is an investigational unimolecular dual agonist developed by Boehringer Ingelheim (licensed from Zealand Pharma) that activates both the glucagon-like peptide-1 receptor (GLP-1R) and glucagon receptor (GCGR)

however, some individuals may experience mild skin sensitivity depending on: Formulation concentration Skin type Frequency of cosmetic application Concurrent cosmetic ingredients Possible Cosmetic Reactions Mild redness Temporary tingling sensations Skin irritation Dryness Increased skin sensitivity Temporary blue discoloration when higher concentrations are utilized Higher concentrations are not always preferred and may increase the likelihood of cosmetic skin irritation, particularly in sensitive-skin formulations

But, these transfusions can cause iron overload