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Subcutnea sistmica (investigacin) : 13 mg/da

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Dulaglutide (Trulicity) achieves once-weekly dosing through a fusion protein strategy (linking the GLP-1 analogue to an IgG4 Fc fragment), producing a half-life of approximately 5 days and a Tmax of 24 to 72 hours 15

The lack of sterile procedures in the making of these drugs has resulted in everything from localized infection at injection sites to systemic shock states