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"This medication has led to significant amounts of weight loss, but when it stops, patients have reported gaining up to two-thirds of that weight back," Sutton said, citing published research

Prescribers initiating BPC-157 in patients with Child-Pugh A or B hepatic impairment should document: (1) the clinical rationale for peptide therapy, (2) the absence of an FDA-approved alternative for the target condition, (3) baseline hepatic function with planned monitoring intervals, and (4) the patient's informed consent acknowledging the investigational nature of the therapy and the specific evidence limitations in their population

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In addition, frequently, physiological events cover more than two organ functions