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The Diabetes Control and Complications Trial (DCCT), a prospective randomized controlled trial of intensive (mean A1C about 7% [53 mmol/mol]) versus standard (mean A1C about 9% [75 mmol/mol]) glycemic control in patients with type 1 diabetes, showed definitively that better glycemic control is associated with 5076% reductions in rates of development and progression of microvascular (retinopathy, neuropathy, and diabetic kidney disease) complications

The injectable forms of GLP-1 medications deliver nearly 100% of the active compound directly into subcutaneous tissue

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