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Additionally, Tianlongkechuanling (TL) mitigates fibrosis by reducing the expression of multiple arginine cycle enzymes, including arginase-1, CPS1, OTC, ASS1, OAT, ASL, and iNOS, helping to restore the balance between arginase and NO synthase pathways [140]

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SUSTAIN-Japan-sitagliptin: Superior effectiveness (reduction in HbA1c, body weight, FPG, SMBG) of semaglutide over sitagliptin was established in this trial where 308 Japanese subjects received weekly-once s.c