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They work by increasing feelings of fullness, slowing digestion, and reducing appetite all of which can lead to significant weight loss

However, the majority of EECs express several hormones that overlap between different enteroendocrine cells

But the reduction is often disproportionate, hitting protein intake harder than other macronutrients because protein-rich foods tend to be the most satiating and the hardest to consume when appetite is suppressed

Improvements in blood sugar control, triglycerides, and systolic blood pressure stayed about the same after the reduced dosing