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Additional Glacial Acetic Acid and/or Sodium Acetate may have been used to adjust pH

We note that, for purposes of identifying significant procedure codes for examination under the 2 times rule, we consider procedure codes that have more than 1,000 single major claims or procedure codes that both have more than 99 single major claims and contribute at least 2 percent of the single major claims used to establish the APC cost to be significant (75 FR 71832)

FIGURE 1 Complex I (cI) is an NADH-ubiquinone oxidoreductase that pumps four protons into the intermembrane space (IMS) upon each NADH oxidation