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The results of calculations using the Friedewald formula are also less accurate if intermediate density lipoproteins (IDL) are present in the plasma as well as in conditions in which the composition of lipoprotein particles is changed (obesity, type 2 diabetes mellitus, metabolic syndrome, kidney, and liver diseases)

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Wegovy is a glucagon-like peptide-1 (GLP-1) receptor agonist licensed by the MHRA for chronic weight management in adults with obesity or overweight with weight-related comorbidities, as recommended by NICE