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Tesamorelin offers something unusual: preferential reduction of visceral fat while preserving or even increasing lean mass

Some participants achieved weight loss of approximately 24% of body weight at 48 weeks approaching levels reported with some bariatric surgical procedures, though no direct head-to-head comparisons have been conducted and long-term durability beyond the trial period remains unknown

If retatrutide is inadvertently left outside of refrigeration, the consequences depend on several factors: the ambient temperature, the duration of exposure, and whether the product was in its original sealed packaging or already in use

12 , R33 (2010)