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Mice treated with antibiotics or reared germ free are resistant to KD-mediated seizure protection, whereas enrichment of Akkermansia muciniphila and Parabacteroides populations restores anti-epileptic effect of KD (76)

For example, melatonin has been found to stimulate the -secretase cleavage of APP in cultured neuronal and non-neuronal cells [52] via upregulation of the nonamyloidogenic ADAM10 and ADAM17 proteases

Finally, the ongoing SURPASS-CVOT is like the boss battle: the mother of all GLP-1 agonist clinical trials