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The 2024 NICE guideline NG239 sets out a more intensive loading schedule for patients with neurological involvement precisely because their starting point is worse

Chronic low-grade scalp inflammation is now recognized as a driver of multiple hair-loss patterns, including telogen effluvium and diffuse thinning

This is the same directional change sought with FDA-approved therapies like minoxidil, but achieved through a distinct upstream mechanism

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