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Month 6: peak velocity has passed At the six-month mark, you have likely lost 12 to 15 percent of your starting body weight if you reached the full 2.4 mg dose on schedule and responded at or above the average rate

Waterhouse M, Hope B, Krause L, Morrison M, Protani MM, Zakrzewski M, et al

Variants in JAK2, TYK2, STAT1, STAT3, STAT4 genes increase UC susceptibility [19], and JAK3 knockout mice develop severe combined immunodeficiency, affecting T and B cell development, resulting in IEC differentiation defects and impaired intestinal barrier function, thus increasing susceptibility to UC [131]

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