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Studies have noted variations in catalase levels and activity within the brains of individuals with Alzheimers disease, suggesting a potential correlation between catalase dysfunction and neurodegeneration progression [50,51] (Figure 2)

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1c), or for GPP3 in the VP1 hydrophobic pocket, with the latter instead occupied by the naturally acquired lipid from the yeast cell, modelled as sphingosine based on the length of the carbon chain fitting the cryo-EM potential map 33

Addressing clinical needs in NSCLC immunotherapy: mechanisms of resistance and promising combination strategies