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This review provides an analysis of GLP-1 RAs and their multi-agonist derivatives as therapeutic agents for MASLD, examining their biological mechanisms and clinical efficacy based on current evidence

If mood changes are severe or persistent, discontinue use

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1 Introduction Cardiovascular disease (CVD) continues to be a significant global health concern, with ischemic stroke and acute myocardial infarction ranking as the second and third leading causes of death worldwide in 2019 ( The complex interaction between diabetes mellitus (DM) and cardiovascular events complicates patient management