does vitamin b12 injection need to be refrigerated Shots at Home: How, Where & How Often Inject Yourself should b12 injections be refrigerated

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If a pregnant patient has a documented deficiency of one or more B vitamins or a condition like hyperemesis that prevents oral intake, the benefits of correcting the deficiency (preventing serious maternal and fetal complications) outweigh any minimal risk from the injection

Over time, if left untreated, pernicious anemia can cause severe complications such as nerve damage, cognitive problems, and heart issues