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Aging is also associated with an increase in mitochondrial content in memory CD4 + T cells, which leads to the generation of ROS and subsequently promotes the expression of proinflammatory cytokines [299]
Another member of the natriuretic peptide family, A-type natriuretic peptide (ANP), which also has diuresis activity, was shown to be stimulated by exenatide, a GLP-1 receptor agonist (72, 108)
Individual responses vary, which is why baseline colitis assessment and close monitoring during the first 48 weeks of treatment are essential
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