acetyl l carnitine effect on hypothyroidism Acetyl-L-Carnitine 500mg x 100 Capules Acetyl-L-Carnitine: Benefits, Forms, Dosing, and

doi: 10.1016/j.neuron.2006.07.011 318 SakamotoKSuzukiTTakahashiKKoguchiTHirayamaTMoriAet al

2015;149(3):R10314

doi:10.1055/s-2007-973071

Evaluation of: Glycerol production (a marker of lipolysis) 2-deoxyglucose uptake (a marker of insulin signaling) DNA synthesis (a marker of proliferation) What they found: AOD-9604 stimulated lipolysis dose-dependently from 10 M, with a plateau at 10 M Full hGH stimulated lipolysis to a similar maximum, but with different kinetics AOD-9604 did not affect glucose uptake or DNA synthesis at all, whereas hGH inhibited both (the classic lipotoxic GH effect) Fragments with different sequence (from the N-terminal part of hGH) had no lipolytic effect Why it matters: This was the first publication of AOD-9604